By using systematic review method, scientists revealed that higher amount of two types of gut microbiota and a diverse microbiota composition link to better cognitive ability among cognitively healthy seniors. These findings suggest a future possibility of using gut microbiota as a biological marker for detecting Alzheimer’s before cognitive symptoms occur. Microbiota is consist of microorganisms, such […]
Digital clock drawing test as a digital biomarker for early detection of Alzheimer’s disease
By using a digital clock drawing test, called DCTclockTM, researchers found that older adults with genetic risk of Alzheimer’s disease performed worse in the test than those without the risk. The genetic risk of Alzheimer’s in this study means that a person carries the APOE e4 gene or has a higher polygenic risk score. The findings suggest the potential of […]
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8 Min
Blood-based biomarker p-tau217 may revolutionize the diagnosis of Alzheimer’s disease
Blood test of p-tau217 showed a similar or better ability in detecting Alzheimer’s disease-related structure changes in the brains of individuals with impaired cognitive ability, compared with cerebrospinal fluid test. The researchers suggest that p-tau217 blood test may replace positron emission tomography or cerebrospinal fluid test, the methods currently used in research and the clinic. […]
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6 Min
Weakened bones in women and chest pain in men are the top predictors of Alzheimer’s disease, a machine learning model shows
Researchers developed a machine learning model trained on a large amount of electronic health record data for finding risk factors that can predict Alzheimer’s disease. Machine learning model is a computer program that can find patterns in or make predictions about previously unseen data, after people trained it with a set of data. They identified weakened […]
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5 Min
GFAP Predicts Cognitive Worsening of Patients with Impaired Cognitive Ability
A cohort study of patients with impaired cognitive ability suggested that glial fibrillary acidic protein (GFAP), a potential blood-based biological marker, also called biomarker, can predict decline of cognitive ability associated with Alzheimer’s disease. This study showed the power of blood GFAP in predicting cognitive decline among patients with impaired cognitive ability. Current methods used […]
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5 Min
Increased Blood Levels of GFAP May Track Alzheimer’s Disease Progression Before Cognitive Symptoms Occur
In a study with people who had normal cognitive ability, researchers found that the blood levels of glial fibrillary acidic protein (GFAP) increased more rapidly in people at risk of future Alzheimer’s disease than those without the risk of the disease. Protein GFAP locates in the cells that support the nerve cells in the central […]
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5 Min